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Desperate for funds, surgical student Mary applies for work at a strip club, where she meets Billy Barker, the club owner. Billy is in need of a medical professional to patch up a man bleeding in his club's basement, and offers Mary $5,000 to perform emergency surgery. Mary accepts the money, and is then approached by Ruby who wishes to be transformed into a human doll, and has been unable to find a surgeon willing to complete the last step in her transformation. Mary accepts, she’s introduced to the world of extreme body modification. Her teachers and mentors praise her promising skills. Mary is invited by to a networking party. While at the party, she is drugged and abused by her former teacher who films the assault. Mary later drops out of her residency. Mary hires Billy and his enforcers to kidnap Grant and deliver him to her apartment, where she holds him hostage and uses him as practice material for her extreme surgeries. Mary goes into consensual body modification surgery full-time and word spreads quickly through dark web channels that Bloody Mary is a surgeon of great skill willing to perform any extreme surgery desired. Mary is approached by police detective Dolor, who asks about the disappearance of Dr. Grant, explaining that Dr. Walsh gave him a long list of women who might bear a grudge against Dr. Grant, and that Mary was on the list. When Detective Dolor confronts Mary again, believing that she was a victim of one of the sex parties hosted by the two missing doctors and hoping to help her, Mary's mental state is shown to be deteriorating further. Police interest in her causes her concern and she worries that a tape of her rape will be found. Meanwhile, Ruby's husband, vengeful after seeing his newly modified wife, tortures Beatress to near death for Mary’s location before ambushing Mary at her house with a knife. Mary attempts to suture her own wound shut but ultimately bleeds to death in her operating room, to be discovered by the police.

Desperate for funds, surgical student Mary gets into illegal surgery leading to a slow decent into the underbelly of society, getting slowly more affected than she thought.

Desperate for funds, surgical student Mary applies for work at a strip club, where she’s asked to patch up a man bleeding in his club's basement. After Mary accepts to perform the emergency surgery she is then introduced to the world of extreme body modification. After being drugged and abused by her former teacher, Mary drops her residency and goes into consensual body modification surgery. She is then known as Bloody Mary a surgeon of great skill for extreme surgery.

American Mary